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KMID : 0829320120150010001
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Korean Journal of Clinical Microbiology
2012 Volume.15 No. 1 p.1 ~ p.8
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Carbapenem-Resistant Acinetobacter baumannii
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Bae Il-Kwon
Jeong Seok-Hoon
Lee Kyung-Won
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Abstract
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Clinical isolates of Acinetobacter spp. in Korea exhibit higher antimicrobial resistance rates than in foreign countries and frequently show multi-drug resistance. Approximately 67% (272/405) of Acinetobacter baumannii isolates collected from 19 hospitals in Korea in 2008 exhibited intermediate susceptibility or resistance to imipenem and/or meropenem. The most important mechanisms in acquiring carbapenem resistance in A. baumannii in Korea are production of OXA-23 and overproduction of OXA-51, while that in non-baumannii Acinetobacter is the production of metallo-β-lactamases. All the carbapenem-resistant A. baumannii isolates were identified as clonal complex 92 and belonged to worldwide clone 2.
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KEYWORD
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Acinetobacter baumannii, Carbapenem, Worldwide clone 2
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